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. Author manuscript; available in PMC: 2010 May 23.
Published in final edited form as: AIDS. 2010 Mar 13;24(5):659–667. doi: 10.1097/QAD.0b013e328336781d

Figure 5. RNase H cleavage during ATP-mediated AZT-MP excision by WT and mutant HIV-1 RT.

Figure 5

A) Representative autoradiogram of the RNase H cleavage activities of K70R/LM184V and K70R/M184V/N348I HIV-1 RT. The reaction times are 1, 3, 5, 10, 20, 30, 40, 60 and 90 min.

B) Representative autoradiogram of the RNase H cleavage activities of K70R/L74V and K70R/L74V/N348I HIV-1 RT. The reaction times are 1, 3, 5, 10, 20, 30, 60 and 90 min.

C) Representative autoradiogram of the RNase H cleavage activities of WT, N348I, Y181C/N348I, L74V/N348I and M184V/N348I HIV-1 RT. The reaction times are 1, 3, 5, 10, 20, 30, 60 and 90 min.