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. Author manuscript; available in PMC: 2011 Apr 26.
Published in final edited form as: Vaccine. 2010 Mar 4;28(19):3333–3340. doi: 10.1016/j.vaccine.2010.02.089

Table 2. Outcomes at 6 and 36 months follow-up in Trial #1.

Groups Diagnosis at

6 months 36 months


Treatment N Fraction showing initial improvement Fraction surviving (%)
[exact 95% CId]
#
Dead
#
Sick
#
Cured
#
Censorede
% Cured
[exact 95% CI]
Vaccine 18 15/15a 15/15(100%)
[78.2 – 100]
2 1 9 6 75.0
[42.8 – 94.5]
Glucantime 15 12/15 12/15(80.0%)
[51.9 – 95.7]
4 0 7 4 63.6
[30.7 – 89.1]
Vaccine + Glucantime 13 12/13 13/13(100%)
[75.2 – 100]
3 2 5 3 50.0
[18.7 – 81.3]
No treatment 13 0/12b 7/12c(58.3%)
[27.7 – 84.8]
a

Three dogs receiving vaccine died of unrelated causes during the 6 months after vaccination; their causes of death were cardiac infarction, canine distemper, and intoxication. These dogs are listed as censored.

b

One dog in the control group was lost to the study in the first month and was scored as censored.

c

Five dogs in the control group died and one was lost during the initial 6-month period. The remaining seven sick dogs were treated with Glucantime at the 6-month time point and not followed further.

d

CI, confidence interval.

e

Censored dogs include dogs lost to the study or dying of causes other than VL (e.g., osteosarcoma, ehrlichiosis, and those listed above).