Table 2. Outcomes at 6 and 36 months follow-up in Trial #1.
Groups | Diagnosis at | |||||||
---|---|---|---|---|---|---|---|---|
6 months | 36 months | |||||||
Treatment | N | Fraction showing initial improvement | Fraction surviving (%) [exact 95% CId] |
# Dead |
# Sick |
# Cured |
# Censorede |
% Cured [exact 95% CI] |
Vaccine | 18 | 15/15a | 15/15(100%) [78.2 – 100] |
2 | 1 | 9 | 6 | 75.0 [42.8 – 94.5] |
Glucantime | 15 | 12/15 | 12/15(80.0%) [51.9 – 95.7] |
4 | 0 | 7 | 4 | 63.6 [30.7 – 89.1] |
Vaccine + Glucantime | 13 | 12/13 | 13/13(100%) [75.2 – 100] |
3 | 2 | 5 | 3 | 50.0 [18.7 – 81.3] |
No treatment | 13 | 0/12b | 7/12c(58.3%) [27.7 – 84.8] |
Three dogs receiving vaccine died of unrelated causes during the 6 months after vaccination; their causes of death were cardiac infarction, canine distemper, and intoxication. These dogs are listed as censored.
One dog in the control group was lost to the study in the first month and was scored as censored.
Five dogs in the control group died and one was lost during the initial 6-month period. The remaining seven sick dogs were treated with Glucantime at the 6-month time point and not followed further.
CI, confidence interval.
Censored dogs include dogs lost to the study or dying of causes other than VL (e.g., osteosarcoma, ehrlichiosis, and those listed above).