Table 3. Completion of vaccine Trial #2, classified by Clinical Score.
Clinical score | Vaccine | Adjuvant alone | Vaccine + Adjuvant alone | ||||||
---|---|---|---|---|---|---|---|---|---|
Trial completed | *Trial not completed | Total | Trial completed | Trial not completed | Total | Trial completed | Trial not completed | Total | |
≥8 | 0 | 4 | 4 | 0 | 1 | 1 | 0 | 5 | 5 |
<8 | 5 | 1 | 6 | 3 | 1 | 4 | 8 | 2 | 10 |
Total | 5 | 5 | 10 | 3 | 2 | 5 | 8 | 7 | 15 |
**P=0.0476 | **P=0.4 | **P=0.007 |
“Trial not completed” refers to dogs that failed to improve with the study injections and were treated with Glucantime or amphotericin B. Some of these dogs ultimately died from leishmaniasis.
2-tailed Fisher's exact test.