Table 4.

Parasitological evaluations of dogs in Trial #2

	Parasitology^a							CS

Group	D0	D30	D60	D90	D120	D150	D180	Day 0	Endpoint^b
Saline	+	Out	Out	Out	Out	Out	Out	9	8
Saline	+	+	+	-	Out	Out	Out	8	9
Saline	+	+	Out	Out	Out	Out	Out	6	11
Saline	+	+	+	+	Out	Out	Out	6	7
Saline	+	-	-	+	+	-	-	3	4
Adjuvant	+	+	-	+	-	Out	Out	8	6
Adjuvant	+	-	-	Out	Out	Out	Out	7	10
Adjuvant	+	+	-	-	ND	+	ND	7	3
Adjuvant	+	+	+	-	-	+	-	6	3
Adjuvant	+	-	+	-	-	ND	-	4	0
Vaccine	+	+	+	+	Out	Out	Out	12	11
Vaccine	+	+	Out	Out	Out	Out	Out	10	8
Vaccine	+	Out	Out	Out	Out	Out	Out	8	12
Vaccine	+	-	+	Out	Out	Out	Out	8	8
Vaccine	+	+	-	-	-	-	-	7	2
Vaccine	+	ND	ND	-	-	-	-	7	1
Vaccine	+	+	-	Out	Out	Out	Out	6	10
Vaccine	+	-	ND	-	-	-	-	6	6
Vaccine	+	-	-	+	-	-	-	6	0
Vaccine	+	-	-	-	-	-	-	5	1

Parasitology was performed by microscopic observation of a Giemsa-stained smear of spleen, lymph node or ear biopsy, or by culture of spleen aspirate: +, parasite detected in at least one of the samples; -, negative (no parasites detected) in the samples evaluated; ND, not done; Out, the dog was removed from the study either because of no improvement or death of the dog.

CS Endpoint, Clinical Score at the endpoint for each dog, either at the time of removal from the study or Day 180.