Table 4.
Dyskinesia and off periods
|
Baseline |
1 year |
|||||
|---|---|---|---|---|---|---|
| Surgery | Medical therapy | p* | Surgery | Medical therapy | p* | |
| Dyskinesia | ||||||
| n | 177 | 180 | 0·93 | 155 | 151 | <0·0001 |
| None | 19 (11%) | 27 (15%) | .. | 75 (48%) | 21 (14%) | .. |
| 1–25% | 71 (40%) | 63 (35%) | .. | 65 (42%) | 56 (37%) | .. |
| 26–50% | 55 (31%) | 55 (31%) | .. | 10 (6%) | 44 (29%) | .. |
| 51–75% | 26 (15%) | 27 (15%) | .. | 4 (3%) | 27 (18%) | .. |
| 76–100% | 6 (3%) | 8 (4%) | .. | 1 (1%) | 3 (2%) | .. |
| Off time | ||||||
| n | 175 | 180 | 0·40 | 154 | 152 | <0·0001 |
| None | 6 (3%) | 2 (1%) | .. | 45 (29%) | 5 (3%) | .. |
| 1–25% | 66 (38%) | 68 (38%) | .. | 83 (54%) | 64 (42%) | .. |
| 26–50% | 85 (49%) | 88 (49%) | .. | 23 (15%) | 63 (41%) | .. |
| 51–75% | 16 (9%) | 20 (11%) | .. | 3 (2%) | 17 (11%) | .. |
| 76–100% | 2 (1%) | 2 (1%) | .. | 0 (0%) | 3 (2%) | .. |
Based on UPDRS part IV: complications of therapy (Q32: what proportion of the waking day is dyskinesia present? Q39: what proportion of the waking day is the patient off on average?).
*
χ2 test for the difference between the surgery group and the medical therapy group across all categories.