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. Author manuscript; available in PMC: 2010 Dec 14.
Published in final edited form as: Neuroscience. 2009 Aug 31;164(3):941–947. doi: 10.1016/j.neuroscience.2009.08.055

Fig. 2.

Fig. 2

Mean (+/- S.D.) odor discrimination performance after administration of the GABA(B) antagonist CGP55845 or saline vehicle in young adult (open bar), aged learning-unimpaired (solid grey bar), and aged learning-impaired (hatched grey bar) rats. There was a significant Cognitive Age Group by Drug Condition interaction such that treatment with 0.01 and 0.1 mg/kg of CGP558445 improved trials to criterion specifically in the aged learning-impaired group. Black lines indicate means in the subset of rats tested with the 0.001 mg/kg dose, which as shown was ineffective in reversing the learning deficit in the aged learning-impaired group.