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. Author manuscript; available in PMC: 2010 May 24.
Published in final edited form as: Cell Health Cytoskelet. 2009 Sep 16;2009(1):67–80. doi: 10.2147/chc.s5965

Figure 7.

Figure 7

Schematic representation of how N-glycosylation of E-cadherin affects cytoskeletal dynamics. Extensively N-glycosylated E-cadherin/β-catenin complexes associate with less PP2A and dynein compared to hypoglycosylated V13/β-catenin AJs. V13/β-catenin complexes recruit more PP2A, which correlates with dephosphorylation of tau, and most likely dynein, leading to stabilization of MTs. Also, V13/γ-catenin complexes recruit more vinculin, most likely via α-catenin, which promotes the interaction of AJs with the actin filaments.