Table 2.
Second-line chemotherapy regimens and disease control rate.
| Chemotherapy | Single agent doxorubicin | 62 (16.4%) | |||||
| Single agent ifosfamide | 123 (32.5%) | ||||||
| Other Single agent | 106 (28.0%) | ||||||
| Doxorubicin/ifosfamide | 21 (5.5%) | ||||||
| Other combination | 32 (8.4%) | ||||||
| Phase I trial | 35 (9.2%) | ||||||
|
| |||||||
| Number of Cycles | 1 | 2 | 3 | 4 | 5 | 6 | >6 |
| 72 | 111 | 35 | 49 | 16 | 68 | 28 | |
|
| |||||||
| Response | CR | 8 (2.1%) | |||||
| PR | 20 (5.3%) | ||||||
| SD | 76 (20.1%) | ||||||
| PD | 266 (70.2%) | ||||||
| NA | 9 (2.4%) | ||||||
|
| |||||||
| Disease control rate | CR/PR/SD >6 months | 86 (23.2%) | |||||
| Non responder | 284 (76.8%) | ||||||
CR: complete response, PR: partial response, SD: stable disease, PD: progressive disease, NA: not assessable.