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. Author manuscript; available in PMC: 2011 May 21.
Published in final edited form as: Neurosci Lett. 2010 Apr 2;475(3):174–178. doi: 10.1016/j.neulet.2010.03.073

Figure 3. The effect of non-neurotoxic variants of HIV-1 Tat (Cys22 Tat 1–86 B and Tat 1–101 C) on the Aβ 1–42 production in hippocampal cell cultures.

Figure 3

The graph represents results of direct anti-Aβ 1–42 ELISA measurements in the CM samples collected from individual cultures (n=8 per group) treated with 100 nM Tat 1–86 B, Cys22 Tat 1–86 B, Tat 1–101 C, or the equal volume of vehicle for 72 hours. Data are presented as mean values ± SEM. Cell viability in hippocampal cell cultures was determined using Live/Dead assay. *- marks significant (P<0.05) differences in hippocampal cell viability or extracellular Aβ 1–42 immunoreactivity.