Table 1.
Demographic, Clinical and Pathologic Characteristics for the 151 Patients
| Variable | Total (n=151) | Relapse (n=47) | Non-relapse (n=104) | P value |
|---|---|---|---|---|
| Age (yrs) | ||||
| Mean (± SD) | 58.5 (± 6.1) | 58.8 (± 5.5) | 58.3 (± 6.4) | 0.703* |
| Median (range) | 59.0 (41 – 71) | 59.0 (47 – 69) | 60.0 (41 – 71) | |
|
| ||||
| Race | ||||
| Caucasian | 141 (93.4) | 43 (91.5) | 98 (94.2) | 0.503 |
| Non Caucasian | 10 (6.6) | 4 (8.5) | 6 (5.8) | |
|
| ||||
| Clinical stage | ||||
| T1a | 1 (0.7) | 0 (0) | 1 (1.0) | 0.326 |
| T1b | 4 (2.7) | 1 (2.1) | 3 (2.9) | |
| T1c | 66 (43.7) | 18 (38.3) | 48 (46.1) | |
| T2a | 44 (29.1) | 16 (34.0) | 28 (26.9) | |
| T2b | 23 (15.2) | 7 (14.9) | 16 (15.4) | |
| T2c | 11 (7.3) | 4 (8.5) | 7 (6.7) | |
| T3a | 2 (1.3) | 1 (2.1) | 1 (1.0) | |
|
| ||||
| Preoperative PSA | ||||
| ≤ 4.01 | 27 (17.9) | 3 (6.4) | 24 (23.1) | < 0.0001* |
| 4.0 – 10.0 | 80 (53.0) | 15 (31.9) | 65 (62.5) | |
| 10.0 – 20.0 | 35 (23.1) | 24 (51.1) | 11 (10.6) | |
| > 20.0 | 9 (6.0) | 5 (10.6) | 4 (3.8) | |
|
| ||||
| Postoperative Gleason score | ||||
| 0 - Gleason sum 5 | 5 (3.3) | 0 (0) | 5 (4.8) | < 0.0001* |
| 1 - Gleason pattern 3+3 | 61 (40.4) | 4 (8.5) | 57 (54.8) | |
| 2 - Gleason pattern 3+4 | 49 (32.4) | 15 (31.9) | 34 (32.7) | |
| 3 - Gleason patter 4+3 | 16 (10.6) | 13 (27.7) | 3 (2.9) | |
| 4 - Gleason sum 8–10 | 20 (13.3) | 15 (31.9) | 5 (4.8) | |
|
| ||||
| Extra capsular penetration | ||||
| No | 82 (54.3) | 9 (19.1) | 73 (70.2) | < 0.0001 |
| Yes | 69 (45.7) | 38 (80.9) | 31 (29.8) | |
|
| ||||
| Surgical margin involvement | ||||
| No | 117 (77.5) | 27 (57.5) | 90 (86.5) | < 0.0001 |
| Yes | 34 (22.5) | 20 (42.5) | 14 (13.5) | |
|
| ||||
| Lymph node involvement | ||||
| No | 133 (88.1) | 31 (66.0) | 102 (98.1) | < 0.0001 |
| Yes | 18 (11.9) | 16 (34.0) | 2 (1.9) | |
|
| ||||
| Seminal vesicle involvement | ||||
| No | 131 (86.7) | 29 (61.7) | 102 (98.1) | < 0.0001 |
| Yes | 20 (13.3) | 18 (38.3) | 2 (1.9) | |
*
Analyzed using t test or nonparametric Wilcoxon rank sum test for continuous data;
Numbers shown are frequencies with percentages in parentheses except for age.