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. 2010 Feb 25;38(9):e111. doi: 10.1093/nar/gkq089

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Summary of characteristics of neighbourhood hybridization intensity profiles for different type of calls. Summary of the characteristics of the NHIP for five types of call: (a) true-non-mutation, (b) true-mutation, (c) isolated error or ‘N’, (d) long chains of consecutive errors or ‘N’, (e) unknown error or ‘N’) based on their respective observed neighbourhood hybridization intensity profiles. The PM probe (red circle) of query base is at position 0 while neighbourhood PM probes (black circles) are numbered according to their distance away from the query base. A PM probe is significantly differentiated from its MM probes if its hybridization intensity is at least t-fold that of all its MM probes.