Figure 3.
Sequence alignment of U13 snoRNAs. (A) The three plant U13 orthologues are aligned with human U13. Identical sequences are indicated by asterisks; for the three plant genes, sequence differences from snoR105 are highlighted white on black. Box C and D sequences are boxed; the two highly conserved regions in the plant genes are shaded grey; the two regions of complementarity to 18S rRNA in human U13 are boxed and labelled A and B [following human model: ref. (48)] and putative inverted repeats adjacent to boxes C and D are shown by arrows. (B) Putative base-pairing interactions between human U13snoRNA and Arabidopsis U13 (snoR146) with the 3′ regions of their cognate 18S rRNAs.