Figure 7.

Fluorescence images of Cy3-labeled random-sequence linear ODN probe showing that the ODN probes are not inside the mitochondrial inner membrane. After delivery of 1 µM of Cy3-labeled random-sequence linear ODN probes, HDF cells were incubated for 24 h. Cells were further incubated without (A and C) or with (C and D) 2 µM of quencher-conjugated linear complementary target, and imaged at 1 h (A and C) or 24 h (B and D) after target delivery. The same exposure time was used for all images.