Table 2.
Association between selected variables and GFR at 12 months (intercept) and GFR slope (multivariate analysis)
| Variable | Coefficient ± ES | t | P |
|---|---|---|---|
| Variables affecting intercept | |||
| Recipient gender (male/female) | −1.523 ± 0.394 | −3.868 | 0.000 |
| HCV status (negative/positive) | −1.789 ± 0.567 | −3.153 | 0.002 |
| Donor age (years) | −0.222 ± 0.012 | −17.927 | 0.000 |
| Delayed graft function | −0.804 ± 0.412 | −1.954 | 0.050 |
| Acute rejection (no/yes) | −2.179 ± 0.421 | −5.179 | 0.000 |
| eGFR at 3 months (mL/min/1.73 m2) | 0.604 ± 0.011 | 52.264 | 0.000 |
| Proteinuria at 12 months (g/24 h) | −0.438 ± 0.067 | −6.516 | 0.000 |
| Systolic blood pressure at 12 months (mmHg) | −0.024 ± 0.010 | −2.389 | 0.017 |
| Variables affecting slope | |||
| Recipient gender by time | −0.505 ± 0.103 | −4.916 | 0.000 |
| Time on dialysis (years) by time | −0.201 ± 0.052 | −3.871 | 0.000 |
| HCV status (vs negative) by time | −0.407 ± 0.136 | −3.001 | 0.003 |
| Primary renal disease (vs diabetes) by time | |||
| Chronic glomerulonephritis | 1.051 ± 0.274 | 3.829 | 0.001 |
| Interstitial nephritis | 0.750 ± 0.324 | 2.314 | 0.000 |
| Nephroangiosclerosis | 1.028 ± 0.294 | 3.491 | 0.000 |
| Polycystic disease | 1.301 ± 0.293 | 4.442 | 0.000 |
| Unknown/other | 0.993 ± 0.276 | 3.596 | 0.000 |
| eGFR at 3 months (mL/min/1.73 m2) by time | −0.023 ± 0.003 | −8.945 | 0.000 |
| Proteinuria at 12 months (mg/day) by time | −0.098 ± 0.018 | −5.545 | 0.000 |
| Immunosuppression 12 months (vs cyclosporine) by time | |||
| Tacrolimus | 0.415 ± 0.193 | 2.147 | 0.032 |
| No calcineurin inhibitors | 0.874 ± 0.341 | 2.562 | 0.010 |
HCV, hepatitis C virus.