. Author manuscript; available in PMC: 2010 Aug 1.

Published in final edited form as: Gene Ther. 2009 Nov 5;17(2):281–287. doi: 10.1038/gt.2009.132

Table 1.

Comparison of cytotoxicity of vaccinia virus in normoxia and hypoxia

Cell Lines	EC50 (95% CI)				P Value	Hill Slope
Cell Lines	20% Oxygen		1% Oxygen		P Value	20% Oxygen	1% Oxygen
Panc1	1.21	(1.03 to 1.41)	0.82	(0.71 to 0.95)	= 0.07	1.075	0.9662
Suit2	1.50	(1.24 to 1.81)	1.88	(1.37 to 2.59)	= 0.48	0.924	1.12
MiaPaca2	187.00	(154.39 to 226.37)	9.15	(7.24 to 11.58)	< 0.00004	0.9555	0.6065
CFPac1	3.89	(3.59 to 4.20)	1.10	(1.04 to 1.16)	<0.002	1.66	1.122

The EC50 values of Vaccinia Virus in the four different pancreatic cancer cell lines is presented with 95% confidence intervals and P values represent any significant difference between infection in normoxia versus hypoxia. Hill slope values for the dose response curves are also presented.