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. Author manuscript; available in PMC: 2010 May 24.
Published in final edited form as: Clin Cancer Res. 2009 Mar 10;15(6):2091–2097. doi: 10.1158/1078-0432.CCR-08-2036

Table 2. FISH results for androgen receptor (AR)*, MYC**, and MYC/8p*** results.

AR FISH results

Amplification Copy Gain NAD Total
No. of patients (%) 17 (34.7%) 13 (26.5%) 19 (38.8%) 49
Median CTC counts
(1st–3rd quartiles)
90
(39–114)
26
(12–86)
4
(3–10)
26.5
(5–99.5)

CTC <10 (%) 0 3 (20%) 12 (80%) 15
CTC ≥10 (%) 17 (50%) 10 (29.4%) 7 (20.6%) 34
MYC FISH results

No. of patients (%) 1 (1.9%) 32 (59.3%) 21 (38.9%) 54
Median CTC counts
(1st–3rd quartiles)
11 53
(24–101)
5.5
(2–39)
27
(6–86.5)

CTC <10 (%) 0 4 (25%) 12 (75%) 16
CTC ≥10 (%) 1 (2.6%) 28 (73.7%) 9 (23.7%) 38
Gain MYC,
8p ratio >=1.5
Gain MYC,
8p ratio 1
NAD Total

No. of patients (%) 24
(55.8%)
5
(11.6%)
14
(32.6%)
43
Median CTC counts
(1st–3rd quartiles)
72
(32.3–107.3)
55
(12–86)
10
(2–27)
24
(11–90)

CTC <10 (%) 0 1 (12.5%) 7 (87.5%) 8
CTC ≥10 (%) 24 (68.6%) 4 (11.4%) 7 (20%) 35
*

No result was obtained from 5 samples, median CTC number 56 (IQR 28–271).

**

Abnormalities were seen in 33 of 54 patients successfully analyzed. No result was obtained from 10 samples, median CTC number 46.5 (IQR 24–294).

***

No result was obtained from 6 samples, median CTC number 24 (IQR 9–135). NAD = no abnormality detected.