Table 2. FISH results for androgen receptor (AR)*, MYC**, and MYC/8p*** results.
AR FISH results | ||||
---|---|---|---|---|
Amplification | Copy Gain | NAD | Total | |
No. of patients (%) | 17 (34.7%) | 13 (26.5%) | 19 (38.8%) | 49 |
Median CTC counts
(1st–3rd quartiles) |
90 (39–114) |
26 (12–86) |
4 (3–10) |
26.5 (5–99.5) |
| ||||
CTC <10 (%) | 0 | 3 (20%) | 12 (80%) | 15 |
CTC ≥10 (%) | 17 (50%) | 10 (29.4%) | 7 (20.6%) | 34 |
MYC FISH results | ||||
---|---|---|---|---|
No. of patients (%) | 1 (1.9%) | 32 (59.3%) | 21 (38.9%) | 54 |
Median CTC counts
(1st–3rd quartiles) |
11 | 53 (24–101) |
5.5 (2–39) |
27 (6–86.5) |
| ||||
CTC <10 (%) | 0 | 4 (25%) | 12 (75%) | 16 |
CTC ≥10 (%) | 1 (2.6%) | 28 (73.7%) | 9 (23.7%) | 38 |
Gain MYC, 8p ratio >=1.5 |
Gain MYC, 8p ratio 1 |
NAD | Total | |
---|---|---|---|---|
No. of patients (%) | 24 (55.8%) |
5 (11.6%) |
14 (32.6%) |
43 |
Median CTC counts
(1st–3rd quartiles) |
72 (32.3–107.3) |
55 (12–86) |
10 (2–27) |
24 (11–90) |
| ||||
CTC <10 (%) | 0 | 1 (12.5%) | 7 (87.5%) | 8 |
CTC ≥10 (%) | 24 (68.6%) | 4 (11.4%) | 7 (20%) | 35 |
No result was obtained from 5 samples, median CTC number 56 (IQR 28–271).
Abnormalities were seen in 33 of 54 patients successfully analyzed. No result was obtained from 10 samples, median CTC number 46.5 (IQR 24–294).
No result was obtained from 6 samples, median CTC number 24 (IQR 9–135). NAD = no abnormality detected.