Table 2. Familial aggregation estimates by specific bowel habit.
No. of families | % With positive family history of same bowel habit | % Relatives with same bowel habit | ||||||
---|---|---|---|---|---|---|---|---|
Cases | Controls | Case-family (%) | Control-family (%) | OR (95% CI) | Case-relatives (%) | Control-relatives (%) | ORa (95% CI) | |
Diarrhea proband | 130 | 297 | 16 | 10 | 1.65 † (0.91–3.00) | 7 | 4 | 1.80* (1.01–3.23) |
Constipated proband | 81 | 297 | 33 | 23 | 1.72* (1.00–2.93) | 14 | 9 | 1.70* (1.10–2.61) |
Alternating proband | 220 | 297 | 68 | 59 | 1.53* (1.06–2.20) | 41 | 31 | 1.52* (1.52–1.92) |
CI, confidence interval; OR, odds ratio.
P = 0.10.
P < 0.05.
Accounts for familial relatedness/dependency.