Fig. 1.

Immune responses against mycobacterial infection. Mycobacteria, recognized by scavenger, mannose, and toll-like receptors, are phagocytosed to eliminate bacilli and processed for T-cell presentation, thus mounting adaptive immune responses. Immediate responses by the innate immune system have a decisive influence on host adaptive response against mycobacterial infection. The characteristic adaptive immune response against mycobacterial infection includes strong Th1 responses and granuloma formation