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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: J Thorac Cardiovasc Surg. 2009 Dec 28;139(6):1609–1617. doi: 10.1016/j.jtcvs.2009.08.060

Figure 1.

Figure 1

Transthoracic echocardiography showing development of LV hypertrophy and later decompensation. (A) Increase in Mass/Volume (M/V) ratio indicating peak hypertrophy in the banded animals occurred at 4–5 wks of age followed by ventricular dilatation at 6wks of age evidenced by a decrease in M/V ratio. (B) Contractile performance was assessed by fractional shortening (FS). The FS was preserved during hypertrophy at 4wks of age and decreased as the ventricle dilated at 6wks (n=6–11, * = p<0.05). (C) There was no significant difference in animal body weights. Banded animals at 6wks of age had no clinical signs of heart failure such as ascites or pleural effusions.