Skip to main content
. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: J Thorac Cardiovasc Surg. 2009 Oct 9;139(6):1587–1593. doi: 10.1016/j.jtcvs.2009.08.016

Figure 4b.

Figure 4b

Bar graft depicting associated changes in VEGF secretion (pg/ml) with overexpression of individual OPN isoforms compared to pCMV empty vector controls on in four NSCLC cell lines. Asterisk denotes a significant difference between OPN isoform and pCMV controls. Mean VEGF concentrations ± standard deviation and p-value are listed below bar graft. H153 and H358 have low native OPN expression and A549 and H460 have high native OPN expression. Significant increases in VEGF secretion were associated with OPNa overexpression compared to controls. Conversely, OPNc overexpression was associated with in significant decreases in VEGF secretion compared to controls in all cell lines. OPNb overexpression was associated with no significant change in VEGF secretion in any of the four cell lines.