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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: J Thorac Cardiovasc Surg. 2009 Oct 9;139(6):1587–1593. doi: 10.1016/j.jtcvs.2009.08.016

Figure 4c.

Figure 4c

Bar graft depicting the effect of the overexpression of individual OPN isoforms compared to pCMV empty vector controls on OPN secretion (pg/ml) in four NSCLC cell lines. Asterisk denotes a significant difference between OPN isoform overexpression in cell lines and pCMV controls. Mean OPN concentrations ± standard deviation and p-value are listed below bar graft. In H153, H358 and H460 overexpression of OPNa and OPNb had no significant impact on OPN protein concentrations in conditioned media. In A549 overexpression of OPNa and OPNb caused significant step-up in OPN protein secretion. Overexpression of OPNc caused a significant increase in OPN secretion in all cell lines.OPN protein is measured by ELISA which is not isoform specific.