Table 4.
Glycemic control, insulin profile and lipid profile pre- and post-exercise intervention
| T2D | OB | |||
|---|---|---|---|---|
| Pre | Post | Pre | Post | |
| Glycemic control | ||||
| Fasting glucose (mmol/L) | 7.2 ± 0.2 | 6.9 ± 0.3 | 5.0 ± 0.2 | 5.0 ± 0.2† |
| Glucose AUC (min·mmol/L) | 2469 ± 94 | 2374 ± 92 | 1403 ± 77 | 1374 ± 75† |
| HbA1c (%) | 7.2 ± 0.3 | 7.1 ± 0.2 | 5.7 ± 0.2 | 5.3 ± 0.1† |
| Insulin profile | ||||
| Fasting insulin (pmol/L) | 78.3 ± 1.2 | 84.9 ± 1.2 | 58.9 ± 1.1 | 42.5 ± 1.2† |
| Insulin AUC (min·pmol/L) | 51880 ± 1 | 58884 ± 1 | 60953 ± 1 | 50582 ± 1‡ |
| ISI | 3.3 ± 1.2 | 2.7 ± 1.2 | 3.9 ± 1.1 | 5.4 ± 1.1†‡ |
| Lipid profile | ||||
| Total cholesterol (mg/dL) | 188 ± 10 | 193 ± 9 | 222 ± 8 | 203 ± 7‡ |
| LDL-c (mg/dL) | 108 ± 9 | 117 ± 8 | 142 ± 7 | 125 ± 7†‡ |
| HDL-c (mg/dL) | 43 ± 13 | 44 ± 14 | 51 ± 15 | 48 ± 14 |
| TGL (mg/dL) | 183 ± 83 | 164 ± 71 | 159 ± 53 | 145 ± 65 |
Values are means ± SE. The insulin-related variables were not normally distributed and therefore, they were log transformed for the statistical analysis and were back-transformed for tabular presentation.
†
p<0.05, group effect (T2D vs. OB);
‡
p<0.05, time (pre- vs. post-training) by group (T2D vs. OB) effect.
T2D, subjects with type 2 diabetes; OB, obese subjects; AUC, area under the curve; ISI, insulin sensitivity index; LDL-c, low density lipoprotein cholesterol; HDL-c, high density lipoprotein cholesterol; TRG, triglycerides