Table 2.
Percentage of G1 and S + G2 phases in MCF-10A cells replated from control and 4 d 4-Cl-BQ +/− PEG-CAT/PEG-SOD treated quiescent cells
| Treat- ment(3μM) | 0 h | 18 h | 26 h | |||
|---|---|---|---|---|---|---|
| Cell cycle phase | G1 | S + G2 | G1 | S + G2 | G1 | S + G2 |
| Control | 95 ± 1.9 | 5 ± 2.3 | 71 ± 2.2 | 29 ± 2.7 | 67 ± 3.2 | 33 ± 2.3 |
| 4-Cl-BQ | 93 ± 1.7 | 7 ± 2.1 | 88 ± 2.8 | *12 ± 2.5 | 87 ± 3.0 | *13 ± 3.1 |
| 4-Cl-BQ + PEG | 92 ± 0.9 | 8 ± 1.1 | 84 ± 1.3 | *16 ± 1.9 | 82 ± 2.2 | *18 ± 1.7 |
| 4-Cl-BQ + PEG-CAT | 92 ± 2.1 | 8 ± 1.9 | 69 ± 2.3 | 31 ± 2.3 | 66 ± 3.6 | 34 ± 2.8 |
| 4-Cl-BQ + PEG-SOD | 93 ± 1.8 | 7 ± 1.6 | 73 ± 3.5 | 27 ± 3.1 | 70 ± 3.6 | 30 ± 2.9 |
| 4-Cl-BQ + PEG- SOD/CAT | 93 ± 2.4 | 7 ± 1.8 | 73 ± 2.9 | 27 ± 3.0 | 64 ± 2.8 | 36 ± 3.3 |
Average ± SD, n=3, p<0.05; Asterisks represent statistical significance relative to untreated control