Table 3.
Depression Outcomes
| Adjusted Analysis | |||||
|---|---|---|---|---|---|
| n (%) | OR (95% CI) | Wald χ2[df=1] | P | ||
| Intervention |
EUC |
Intervention versus EUC* |
|||
| Adults age 60 and older | |||||
| 50% PHQ-9 reduction | |||||
| • 6-month follow-up | 74 (52.5) | 59 (40.1) | 1.70 (1.06 - 2.74) | 4.82 | 0.03 |
| • 12-month follow-up | 70 (56.0) | 58 (45.0) | 1.65 (0.99 - 2.73) | 3.72 | 0.06 |
| Major depression PHQ-9 ≥10 | |||||
| • 6-month follow-up | 50 (35.5) | 73 (49.7) | 0.49 (0.30 - 0.81) | 7.72 | 0.01 |
| • 12-month follow-up | 41 (32.8) | 53 (41.1) | 0.61 (0.35 - 1.05) | 3.13 | 0.08 |
| Adults age 18-59 | |||||
| 50% PHQ-9 reduction | |||||
| • 6-month follow-up | 137 (55.5) | 100 (43.7) | 1.61 (1.12 - 2.32) | 6.47 | 0.02 |
| • 12-month follow-up | 136 (59.9) | 90 (47.4) | 1.65 (1.12 - 2.45) | 6.28 | 0.02 |
| Major depression PHQ-9 ≥10 | |||||
| • 6-month follow-up | 78 (31.6) | 87 (38.0) | 0.67 (0.45 - 0.99) | 4.00 | 0.05 |
| • 12-month follow-up | 65 (28.6) | 67 (35.3) | 0.66 (0.43 - 1.01) | 3.59 | 0.06 |
| Age 60+ | Age 18-59 | Old versus Young** | |||
| 50% PHQ-9 reduction | |||||
| • 6-month follow-up | 133 (46.2) | 237 (49.8) | 1.12 (0.75 - 1.67) | 0.32 | 0.58 |
| • 12-month follow-up | 128 (50.4) | 226 (54.2) | 1.34 (0.87 - 2.06) | 1.73 | 0.19 |
| Major depression PHQ-9 ≥10 | |||||
| • 6-month follow-up | 123 (42.7) | 165 (34.7) | 0.82 (0.54 - 1.27) | 0.78 | 0.38 |
| • 12-month follow-up | 94 (37.0) | 132 (31.7) | 0.72 (0.44 - 1.16) | 1.84 | 0.18 |
*
Logistic regression models are adjusted for baseline PHQ-9 score and type of trial.
**
Logistic regression models are adjusted for baseline PHQ-9 score, type of trial, and intervention status.
EUC indicates enhanced usual care; OR, odds ratio; CI, confidence interval. Number of participants in adults age 60 and older: 6-month n=288, 12-month n=254. Number of participants in adults age 18-59: 6-month n=476, 12-month n=417.