Fig 5.

Representative micrographs of GraL of WT (a1, a2) and MAOB KO (b1,b2) mice and bar graphs (c) illustrate that Amph decreased the numbers of somata that show coexistence of GAD₆₇ and pCREB in the granule cell layer (GraL). Double immunostaining of pCREB and GAD₆₇ was conducted on the OlfB sections of WT and KO mice at 4 h post-repeated saline or Amph treatment, as described in the Methods. The numbers were counted of positively single-immunostained somata (arrowheads) and dually stained somata (arrows). The percents were determined by dividing the numbers of dually stained somata with the total numbers of somata containing either of the proteins. *: significantly different from the value of saline-treated WT mice, p<0.05. #: significantly different from saline-treated MAOB KO.