Table 3.
Maternal characteristics and psychosocial measures and log CRH levels in POUCH Sub-cohort women (N=1216) a
| Mean difference (95% CI) in log CRH (pg/ml)b | ||||
|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Model 4 | |
| Race | ||||
| African Americans vs. Whites | −0.39 (−0.48, −0.30)c | −0.40 (−0.49, −0.31)c | −0.38 (−0.48, −0.28)c | −0.39 (−0.49, −0.29)c |
| Maternal Education (years) | ||||
| <12 vs. >=12 | −0.20 (−0.32, −0.07)c | −0.20 (−0.32, −0.07)c | −0.20 (−0.33, −0.08)c | −0.19 (−0.31, −0.07)c |
| Maternal Weight (per 10 pound increase) | −0.03 (−0.04, −0.02)c | −0.03 (−0.04, −0.02)c | −0.03 (−0.04, −0.02)c | −0.03 (−0.04, −0.02)c |
| Depressive Symptoms and Antidepressant Meds Use | ||||
| CES-D<16 and Meds: No (referent) | ||||
| CES-D<16 and Meds: Yes | −0.09 (−0.33, 0.15) | |||
| CES-D>=16 and Meds: No | −0.13 (−0.22, −0.03)c | |||
| CES-D>=16 and Meds: Yes | −0.06 (−0.31, 0.20) | |||
| Perceived Stress Quartiles | ||||
| Q1 (referent) | ||||
| Q2 | 0.05 (−0.07, 0.17) | |||
| Q3 | 0.01 (−0.12, 0.15) | |||
| Q4 | −0.12 (−0.25, 0.02) | |||
| Anomie Quartiles | ||||
| Q1 (referent) | ||||
| Q2 | −0.04 (−0.16, 0.07) | |||
| Q3 | −0.09 (−0.22, 0.04) | |||
| Q4 | −0.09 (−0.22, 0.05) | |||
| Hostility Quartiles | ||||
| Q1 (referent) | ||||
| Q2 | −0.06 (−0.18, 0.06) | |||
| Q3 | −0.08 (−0.24, 0.08) | |||
| Q4 | −0.10 (−0.24, 0.03) | |||
Abbreviations: CRH = corticotropin-releasing hormone, CI= Confidence Interval, Meds = medications
a
Data missing for some psycosocial variables for 2 to 15 women
b
Weighted for sampling scheme and adjusted for gestational week at blood sampling and all other variables listed in the table
c
p<0.05compared to referent group