Table 3.
Physical function outcomes by intervention arm at baseline and follow-up.
| Variable | P value TET vs LAP, average effect across all follow-up visits | ||||
|---|---|---|---|---|---|
| Baseline | 3 Mo | 6 Mo | 12 Mo | ||
| Six-min Walk (m) | |||||
| TET | 410.7 | 428.7 ± 8.3 (0.03) | 439.8 ± 9.9 (<0.01) | 430.5 ± 10.0 (0.05) | 0.41 |
| LAP | 410.7 | 434.8 ± 8.8 (<0.01) | 426.7 ± 10.3 (0.12) | 408.1 ± 10.5 (0.81) | |
| P value, TET vs LAP | 0.61 | 0.36 | 0.13 | ||
| Stair Climb (sec) | |||||
| TET | 15.1 | 14.0 ± 0.5 (0.02) | 14.1 ± 0.6 (0.07) | 14.3 ± 0.6 (0.17) | 0.54 |
| LAP | 15.1 | 14.7 ± 0.5 (0.37) | 14.6 ± 0.6 (0.39) | 14.5 ± 0.6 (0.30) | |
| P value, TET vs LAP | 0.36 | 0.52 | 0.83 | ||
| SPPB | |||||
| TET | 10.6 | 11.0 ± 0.2 (0.01) | 11.0 ± 0.2 (0.04) | 11.2 ± 0.2 (<0.01) | 0.61 |
| LAP | 10.6 | 11.0 ± 0.2 (0.03) | 11.4 ± 0.2 <0.01) | 11.1 ± 0.2 (<0.01) | |
| P value, TET vs LAP | 0.89 | 0.11 | 0.81 | ||
| Four Meter Walk (sec) | |||||
| TET | 3.9 | 3.5 ± 0.1 (<0.01) | 3.6 ± 0.1 (<0.01) | 3.5 ± 0.1 (<0.01) | 0.80 |
| LAP | 3.9 | 3.6 ± 0.1 (<0.01) | 3.5 ± 0.1 (<0.01) | 3.5 ± 0.1 (<0.01) | |
| P value, TET vs LAP | 0.68 | 0.54 | 0.73 | ||
| Chair Rise (sec) | |||||
| TET | 12.8 | 10.2 ± 0.4 (<0.01) | 9.8 ± 0.4 (<0.01) | 10.3 ± 0.4 (<0.01) | 0.74 |
| LAP | 12.8 | 10.5 ± 0.4 (<0.01) | 10.1 ± 0.4 (<0.01) | 10.0 ± 0.4 (<0.01) | |
| P value, TET vs LAP | 0.49 | 0.53 | 0.64 | ||
| Balance (sec) | |||||
| TET | 29.1 | 28.6 ± 0.3 (0.09) | 28.8 ± 0.4 (0.38) | 29.1 ± 0.3 (0.98) | 0.10 |
| LAP | 29.1 | 29.3 ± 0.4 (0.71) | 29.6 ± 0.4 (0.20) | 29.6 ± 0.3 (0.12) | |
| P value, TET vs LAP | 0.16 | 0.13 | 0.27 | ||
All values are estimated least squares means (± standard error of the mean) from repeated measures analysis of covariance adjusted for gender and baseline value. Baseline value is overall mean used to obtain least squares means at follow-up visits. P values for within group analysis comparing follow up visits to baseline values are reported adjacent to individual mean values.