Table 4.
Scaffolds | Physical properties | Amount of bound Biotin-PlnDIV-BSA complexes (mg)† | Biological performance | ||||
---|---|---|---|---|---|---|---|
Average Fiber/Pore size (μm) | DOC (%) | Young modulus (GPa) | F-actin: stress fiber formation | Proliferation rate (%)* 5days/10days | In-growth* (%) | ||
PCL/CHCl3 | 2.93/20.76 | 60.2 | 1.2 | 0.17 | No | 10.8** | 96.9 |
PCL/HFIP | 0.73/9.37 | 36.1 | 1.35 | 0.27 | Yes | 16.9/36.4 | 67.5 |
PCL/gel/HFIP | 1.52/18.59 | 19.8 | 1.58 | 0.23 | Yes | 37.3/92 | 56.4 |
PCL/gel/TFE | 3.74/38.79 | 25.4 | 0.59 | 0.13 | No | 8.0** | 36.8 |
Values after background subtraction.
Percentage of increase over unmodified contro.
Data from 5 days proliferation assay