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. 2010 Mar 23;33(6):1153–1158. doi: 10.2337/dc09-2090

Table 2.

Participants meeting optimal-care goals: cardiovascular risk parameters, medication use, and monthly cost at baseline and 1 year

Baseline
P value Year 1
P value
ILI DSE ILI DSE
n (% of total cohort) 269 (11) 239 (10) 0.93 517 (24) 359 (16) <0.0001
Diabetes
    A1C (%) 6.3 ± 0.4 6.3 ± 0.5 0.92 6.1 ± 0.5 6.3 ± 0.4 <0.0001
    Number of prescribed medications 1.3 ± 0.9 1.4 ± 0.9 0.28 1.1 ± 0.5 1.5 ± 0.9 <0.001
    Monthly cost ($) 74 (33) 86 (33) 0.13 70 (33) 101 (55) <0.001
Hypertension
    Systolic blood pressure (mmHg) 114 ± 10 115 ± 10 0.68 112 ± 10 114 ± 10 <0.0001
    Diastolic blood pressure (mmHg) 65 ± 8 65 ± 8 0.90 63 ± 8 64 ± 8 0.20
    Number of prescribed medications 1.4 ± 1.1 1.3 ± 1.1 0.34 1.4 ± 1.1 1.5 ± 1.1 0.05
    Monthly cost ($) 40 (24) 35 (24) 0.39 37 (24) 40 (24) 0.08
Hyperlipidemia
    LDL cholesterol (mg/dl) 80 ± 15 81 ± 14 0.49 80 ± 15 79 ± 14 0.84
    HDL cholesterol (mg/dl) 43 ± 12 43 ± 12 0.99 47 ± 13 45 ± 12 <0.0001
    Triglycerides (mg/dl) 183 ± 116 180 ± 118 0.40 152 ± 93 166 ± 95 <0.0001
    Non-HDL cholesterol (mg/dl) 114 ± 24 117 ± 24 0.26 107 ± 23 110 ± 21 0.03
    Number of prescribed medications 1.4 ± 1.1 1.3 ± 1.1 0.48 1.4 ± 1.1 1.5 ± 1.1 0.009
    Monthly cost ($) 48 (65) 52 (65) 0.62 47 (65) 54 (65) 0.008
Total medications
    Number of prescribed medications 3.4 ± 1.8 3.5 ± 1.7 0.86 3.2 ± 1.7 3.8 ± 1.6 <0.001
    Monthly cost ($) 163 (139) 172 (142) 0.86 154 (128) 194 (177) <0.001

Data are mean ± SD or frequency (%) and monthly cost data are mean (median), unless otherwise specified. Participants at optimal care defined as participants with A1C <7%, blood pressure <130/80 mmHg, and LDL cholesterol <100 mg/dl as measured at the applicable study visit.