Macroscopic view (a) shows brown discoloration of globus pallidus (arrow), which had a gritty consistency at autopsy. On histology, von Kossa calcium staining (b) and hematoxylin-eosin staining (c-l) show widespread calcification of cerebellum deep regions (b,c, large pleomorphic calcification = arrows, dark compact round calcification = arrowheads), cerebellum blood vessels (d, arrows), dentate nucleus (e, dark round calcification = arrowheads), cerebellum cortex (f, large pleomorphic calcification = arrows), visual cortex (g,h, pleomorphic calcification = arrows, dark round calcification = arrowheads), hippocampal dentate fascia (i,j, arrows), and hemisphere white matter (k,l, perivascular calcification = arrows, dark round calcification in the vicinity of a capillary = arrowheads).