Table 1.
Characteristics of the study group on admission to the intensive care unit in patients with and without a history of insulin-treated diabetes.
| No history of insulin-treated diabetes (n = 2921) |
History of insulin-treated diabetes (n = 226) |
P value | |
|---|---|---|---|
| Age, years, median (IQR) | 64 (49-74) | 66 (55-75) | < 0.01 |
| Sex, male n (%) | 1790 (62) | 130 (58) | 0.2 |
| Medical admission, n (%) | 1301 (45) | 87 (39) | 0.08 |
| Reason for admission | |||
| Digestive/liver | 312 (11.3) | 21 (10.1) | 0.35 |
| Respiratory | 519 (18.8) | 41 (19.7) | 0.71 |
| Cardiovascular | 878 (31.8) | 71 (34.1) | 0.49 |
| Hematological | 26 (0.9) | 1 (0.5) | 0.99 |
| Neurological | 455 (16.5) | 30 (14.4) | 0.5 |
| Renal | 86 (3.1) | 18 (8.7) | < 0.01 |
| Metabolic | 56 (2) | 15 (7.2) | < 0.01 |
| Trauma | 178 (6.4) | 3 (1.4) | < 0.01 |
| Comorbid conditions | |||
| Cancer, n (%) | 390 (13) | 25 (11) | 0.36 |
| Hematological cancer | 67 (2.3) | 2 (0.9) | 0.34 |
| COPD | 317 (10.9) | 23 (10.2) | 0.82 |
| HIV infection | 24 (0.8) | 2 (0.9) | 0.84 |
| Liver cirrhosis | 110 (3.8) | 11 (4.9) | 0.37 |
| Heart failure | 259 (8.9) | 48 (21.2) | < 0.001 |
| Presence of sepsis, n (%) | |||
| Sepsis | 717 (25) | 60 (27) | 0.52 |
| Severe sepsis | 503 (17) | 49 (22) | 0.10 |
| Septic shock | 227 (7.8) | 16 (7.1) | 0.80 |
| Renal failure on admission | 519 (17.8) | 56 (24.8) | 0.01 |
| With hemodialysis | 27 (0.9) | 10 (4.4) | < 0.001 |
| Without hemodialysis | 492 (16.8) | 46 (20.4) | 0.20 |
| Interventions, n (%) | |||
| Mechanical ventilation | 1720 (59) | 130 (58) | 0.73 |
| Hemofiltration | 65 (2) | 8 (4) | 0.24 |
| Hemodialysis | 36 (1) | 13 (6) | < 0.001 |
| Creatinine, mg/dL | 1.42 ± 1.40 | 1.93 ± 1.90 | < 0.001 |
| SAPS II, median (IQR) | 34 (24-46) | 36 (26-49) | 0.02 |
| SOFA score, median (IQR) | 6 (4-9) | 8 (4-10) | < 0.01 |
COPD = chronic obstructive pulmonary disease; IQR = interquartile range; SAPS = simplified acute physiology score; SOFA = sequential organ failure assessment.