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. Author manuscript; available in PMC: 2010 May 25.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2008 Jul 24;49(11):4837–4843. doi: 10.1167/iovs.08-2115

FIGURE 3.

FIGURE 3

CE DNA cross-linking induced by MMC treatment of whole globes. %DNA-in-head was calculated for comets (as in Fig. 2) derived from CE cells after topical MMC treatment of intact goat eyes. (A) 0.02% MMC treatment followed epithelial debridement. (B) MMC treatment followed epithelial debridement and 75 µm stromal ablation. (C) Eyes treated with MMC after epithelial debridement (as in A) were incubated 24 hours at 37°C, to allow DNA repair. *Significant difference from control; ANOVA P < 0.0001, Dunnett P < 0.01. Mean ± SEM.