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. 2010 Feb 18;12(1):R28. doi: 10.1186/ar2935

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Copyright ©2010 Ghosh et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of pentosan polysulfate on proteoglycan synthesis in mesenchymal precursor stem cell micromass cultures. Bar graphs showing the temporal and concentration effects of pentosan polysulfate (PPS) on the biosynthesis of proteoglycans (determined as sulfated glycosaminoglycans (³⁵S-GAGs)) by mesenchymal precursor stem cells (MPCs) in micromass cultures for 5, 7 and 10 days. Data (mean ± standard deviation) presented as percentage of control calculated from the ³⁵S-GAG DPM/μg DNA values at each PPS concentration (n = 6). ^‡P < 0.05, *P < 0.01; **P < 0.001; ***P < 0.0001 relative to control cultures.