Table 2.

Concentration effects of pentosan polysulfate on hyaluronan deposition in human mesenchymal progenitor cell micromass cultures

PPS concentration (μg/ml)	HA concentration (μg/ml)
	Media 7 days	Matrix 7 days	Media 10 days	Matrix 10 days
Control 0.0	1.54 ± 0.03	1.58 ± 0.01	1.55 ± 0.06	2.10 ± 0.03§
0.1	1.34 ± 0.05#	1.76 ± 0.26	1.30 ± 0.08#	1.64 ± 0.07#
0.5	1.34 ± 0.11#	1.74 ± 0.07	1.22 ± 0.17#	1.89 ± 0.01#
1.0	1.09 ± 0.05#	1.98 ± 0.29	1.23 ± 0.06#	2.42 ± 0.32
2.5	1.50 ± 0.17	1.78 ± 0.23	1.32 ± 0.12#	2.24 ± 0.39
5.0	1.28 ± 0.05#	2.16 ± 0.20*	1.33 ± 0.07#	2.27 ± 0.24
10.0	1.25 ± 0.03#	2.39 ± 0.32	0.84 ± 0.09#	2.57 ± 0.31
20.0	1.36 ± 0.05#	2.31 ± 0.33*	1.32 ± 0.06#	2.54 ± 0.04**
Statistical significance	#PPS < control (P < 0.05)	*PPS > control (P < 0.05)	#PPS < control (P < 0.05)	§Matrix > media (P < 0.05), #PPS < control (P < 0.05), **PPS > control (P < 0.005)

Concentration effects of pentosan polysulfate (PPS) on hyaluronan (HA) deposition in the media and matrix of 7-day and 10-day micromass cultures of human mesenchymal progenitor cells (MPCs). Data are mean ± standard deviation of triplicate culture values.