Table 4.
Signs of scrapie-affected goats kept for milk collection or monitoring of clinical progression
| Animal | Days at VLA | Genotype 127-142-211-222-240 |
Breed | Clinical status & signs at arrival | Clinical status & signs prior to cull |
|---|---|---|---|---|---|
| Scrapie positive (LRS only) | |||||
| G08-1472 | 37 | GIRQP/GIRQP | AN | No signs of TSE (difficult to milk)* | No signs of TSE1,4 |
| G08-1427 | 86 | XIRQP/XIRQP | AN | No signs of TSE | No signs of TSE2,4 |
| G08-1396 | 107 | GIRQS/GIRQP | AN | No signs of TSE | Scrapie (see Fig. 1), pruritic activity on camera recordings2,3 |
| G08-1143 | 99 | GIRQS/GIRQS | AN | Inconclusive (ataxia) | Inconclusive (pruritic behaviour on camera recordings)2-4 |
| G08-1389 | 107 | GIRQP/GIRQP | SA | No signs of TSE | Inconclusive (self-induced scratch reflex, pruritic behaviour and abnormal rising on camera recordings)2,3 |
| G08-1465 | 38 | GIRQP/GMRQP | AN | No signs of TSE (difficult to milk)* | Inconclusive (difficult to milk (kicking)1,4 |
| G08-1430 | 106 | GIRQP/GIRQP | AN | Scrapie (positive scratch test) | Scrapie (see Fig. 1)2,3 |
| Scrapie positive (CNS and LRS) | |||||
| G08-1451 | 98 | GIRQP/GMRQP | AN | No signs of TSE | Inconclusive (pruritic behaviour and abnormal rising on camera recordings)2-4 |
| G08-1415 | 98 | GIRQS/GMRQP | TG | No signs of TSE | Inconclusive (prefers to stay close to pen, kicking when hind limbs touched, head tremor at times, hair loss on left flank not previously seen, pruritic activity on camera recordings)2-4 |
| G08-1383 | 99 | GIRQS/GMRQP | SA | No signs of TSE | Inconclusive (inconclusive scratch test)2-4 |
| G08-1365 | 107 | GIRQP/GMRQP | SA | No signs of TSE | Inconclusive (inconclusive scratch test)2,3 |
| G08-1475 | 86 | GIRQP/GIRQP | AN | No signs of TSE (difficult to milk)* | Scrapie (see Fig. 1), difficult to milk (kicking)2-4 |
| G08-1373 | 107 | SIRQP/GIRQP | SA | Inconclusive (head and body tremor) | Scrapie (see Fig. 1)2,3 |
| G08-1447 | 57 | GIRQP/GIRQP | AN | Inconclusive (head tremor, nervous on head tests) | Scrapie (see Fig. 1), difficult to milk (kicking, sitting down), pruritic activity on camera recordings2-4 |
| G08-1340 | 39 | GIRQP/GMRQP | AN | Scrapie (positive scratch test, teeth grinding) | No signs of TSE (negative scratch test)1 |
| G08-1460 | 98 | GIRQP/GIRQP | AN | Scrapie (positive scratch test, repeated startle to auditory stimuli) | Scrapie (see Fig. 1)2-4 |
AN = Anglo-Nubian, SA = Saanen, TG = Toggenburg.
The clinical TSE status on arrival was assessed using the short protocol; for the assessment of the clinical TSE status prior to cull clinical assessments (short1 or long2 protocol), camera recordings3 and behaviour at milking4 were taken into consideration.
* Inconclusive signs if behaviour during milking was included.