Lung cancer epithelial cell adhesion results on the various PLGA samples and borosilicate glass. Data expressed as mean ± standard deviation of the mean.
Notes:
*P < 0.01, **P < 0.05 and **P < 0.1. Less lung carcinoma cells adhered to the PLGA surfaces with an RMS value of 5.42 nm, compared with the surfaces with an RMS value of 2.30 nm (P < 0.05). Comparing the PLGA surfaces with RMS values of 2.30, 2.23, and 5.42 nm, the least cells adhered to the surfaces with an RMS value of 5.42 nm. PLGA surfaces with RMS values of 5.42, 0.62, and 2.23 nm had the least cancer cell adhesion.
Abbreviations: PLGA, poly(lactic-co-glycolic) acid; RMS, root mean square roughness.