Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CHD8 activates TMPRSS2 in an androgen-dependent context. The indicated androgen-independent cell lines were transfected with the specified siRNA constructs. After selection of the transfected cells, cultures were treated with ethanol (EtOH) or 10 nm DHT for 6 h. Total RNA was isolated, and TMPRSS2 expression was analyzed by quantitative RT-PCR.
