Gene expression changes in Bmpr1a and Bmpr1b single- and double-mutant ovaries. A–E, QPCR analysis of candidate genes changes in 3-month-old ovaries from Bmpr1a cKO, Bmpr1b−/−, and Bmpr1a Bmpr1b dKO compared with WT ovaries; F, QPCR analysis of Acvr1 expression in granulosa cells from immature mice of the same genotypes. Data were analyzed using one-way ANOVA and Tukey's honestly significant differences test. Bars with a different letter (a–c) are significantly different at P < 0.05. RQ, Relative quantity of transcript.