Figure 5.

Histology of UL xenografts subjected to hormone withdrawal. Proliferation activity significantly declined in response to withdrawal of E₂ and/or P₄ as assessed by Ki67 expression. PR was also down-regulated in response to E₂ withdrawal. However, UL xenografts did not show sign of tissue degradation or cell death, and expression of ERα and β-actin was maintained without E₂ and/or P₄, even after 8 wk. All histology images were taken under a ×20 objective lens and in the same magnification.