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. 2010 Apr 21;151(6):2713–2722. doi: 10.1210/en.2009-1487

Figure 5.

Figure 5

Hormone status does not affect SAB in nontransgenic mice. WT female mice treated under the same hormone regimen as 3×Tg-AD mice were tested for SAB in the Y-maze at 6 months of age. There were no significant main effects of treatment on either SAB performance (F = 1.2, P = 0.32) (A) or the number of arm entries (F = 0.29, P = 0.93) (B). Sham, Sham-OVX; O, OVX; E, OVX+E2; Pco, OVX+constant P4; E+Pco, OVX+E2+constant P4; Pcy, OVX+cyclic P4; E+Pcy, OVX+E2+cyclic P4. *, P < 0.05 relative to sham-OVX group; #, P < 0.05 relative to OVX.