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. 2010 Apr 8;151(6):2826–2834. doi: 10.1210/en.2009-1446

Figure 1.

Figure 1

Ovulation rates after hCG treatments (A) and estradiol production by preovulatory follicles (B). A, Follicles that reached at least 340 μm in diameter were induced to ovulate by treatment with (4 IU) hCG. Ovulation rates were significantly lower in ERβ-null follicles compared with WT follicles (*, P < 0.05; n = 14–16 per genotype). B, Estradiol was measured in the spent medium after a 48-h accumulation period (before hCG treatment). WT follicles produce significantly higher amounts of estradiol during culture compared with ERβ-null follicles (*, P < 0.001; n = 8 per genotype).