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. 2010 Apr 7;43(2):51–59. doi: 10.1267/ahc.09028

Table 1.

Gene expression which notably changed in kidneys of E12.5 ICAT –/– mice

Increased genes
No. ICAT–/–/ICAT+/+ ratio Common name Description or Product GO biological process; molecular function
1 24.38 p8, B8Ag, CFAg, Caga, MRP8, CP-10 S100 calcium binding protein A8 chemotaxis
2 22.33 p14, Cagb, GAGB, L1Ag, BEE14, MRP14 S100 calcium binding protein A9 actin cytoskeleton reorganization
3 21.17 3930401C23 T-box 4 angiogenesis
4 21.05 BC117090 stefin A1-like protein cysteine protease inhibitor activity
5 20.96 AK089257 predicted gene, EG433016 cysteine protease inhibitor activity
6 17.6 Brx1, Ptx2, Rieg paired-like homeodomain transcription factor 2 Wnt receptor signaling pathway
7 17.07 BC117090 stefin A1-like protein cysteine protease inhibitor activity
8 16.46 Bft, Potx, Ptx1, P-OTX paired-like homeodomain transcription factor 1 cartilage development
9 14.51 islet 2 insulin related protein 2 multicellular organismal development
10 14.14 9930020N01Rik ankyrin repeat and kinase domain containing 1 protein amino acid phosphorylation
11 13.56 Cnlp, MCLP, CAP18, Cramp, FALL39 cathelicidin antimicrobial peptide defense response
12 12.11 Tbx5 T-box 5 emdryonic arm morphogenesis
13 11.5 MGC107339 tetratricopeptide repeat domain 9B protein folding
14 10.44 AK016846 Mus musculus adult male testis cDNA
Decreased genes
No. ICAT–/–/ICAT+/+ ratio Common name Description or Product GO biological process; molecular function
1 0.0991 AI503486, mkIAA0666, E130308H01 dishevelled associated activator of morphogenesis 1 actin cytoskeleton organization and biogenesis
2 0.0928 TLL, Tlx, frc, Mtl1, MTll, XTLL, fierce nuclear receptor subfamily 2, group E, member 1 anterior commissure morphogenesis
3 0.0908 AK038959 Mus musculus adult male hypothalamus cDNA
4 0.0873 2010321J07Rik UDP glucuronosyltransferase 2 family, polypeptide A3 metabolic process
5 0.0849 Cpd2, Caps2 Ca2+-dependent activator protein for secretion 2 exocytosis
6 0.0839 T2R4, T2R07, mGR06, Tas2r7, mt2r43, STC5-1 taste receptor, type 2, member 107 detection of chemical stimulus
7 0.0809 1110014K05Rik late cornified envelope 1C
8 0.074 MOR245-19P olfactory receptor 1307 G-protein coupled receptor protein signaling pathway
9 0.0598 AGT1, XAT2, AGT-1 aspartate/glutamate transporter 1 amino acid transport
10 0.0504 MOR211-1 olfactory receptor 1502 G-protein coupled receptor protein signaling pathway
11 0.0455 AK017313 RIKEN cDNA 5430416B10 gene
12 0.0423 AK028476 RIKEN cDNA A330078L11 gene
13 0.0353 EC-SOD superoxide dismutase 3, extracellular response to hypoxia
14 0.0336 Tac2r tachykinin receptor 2 G-protein coupled receptor protein signaling pathway
15 0.0321 Tsap6, pHyde STEAP family member 3 apoptosis, cell cycle
16 0.0299 RP23-281P6.1 hypothetical protein LOC66328 metabolic process
17 0.029 PTG, Ppp1r5 protein phosphatase 1, regulatory (inhibitor) subunit 3C carbohydrate metabolic process
18 0.0233 NAP022465-001
19 0.02 Rslcan-7, mszf59-2 zinc finger protein 458 reguration of transcription, DNA-dependent
20 0.016 NM_177220 Mus musculus RIKEN cDNA A630031M04 gene integral to membrane