Skip to main content
. Author manuscript; available in PMC: 2011 Apr 13.
Published in final edited form as: Biochemistry. 2010 Apr 13;49(14):3049–3059. doi: 10.1021/bi901953j

FIGURE 1.

FIGURE 1

Spatial relationships for residues investigated. Van der Walls spheres for the side chains of E309 (TM 7) and D398 (TM 10) in the VAChT homology model (16) are viewed from cytoplasm (top) and the center of the membrane (bottom). The first half of the sequence is cyan and the second half is gray. The ACh transport channel is in the center. Carbon atoms are green and carboxyl oxygen atoms are red. Not shown is H338 (TM VIII) interacting with D398, as it has been shown to be not critical (11). The model is rendered in PyMOL.