FIG. 3.

Effect of Shh treatment on the release of proangiogenic factors in cocultures, pOB monocultures, and OEC monocultures. The concentrations of VEGF (A, B), Angiopoietin1 (C, D), and Angiopoietin2 (E, F) in the supernatants of pOBs, OECs, and cocultures consisting of both cell types were measured in an enzyme-linked immunosorbent assay after 24 h and after 14 days of stimulation. Results are demonstrated in percentage ratio (control = 100%; A, C, E) and additionally shown as absolute values (B, D, F). *p < 0.05 and **p < 0.03.