Figure 4.

pFDR analyses. (A) The number of significant probes detected at different q-value thresholds from the regression analyses between DNA methylation changes and four outcome measures of lung function or decline prior to probe selection described herein. (B) The number of significant probes detected at different q-value thresholds after probe selection. A greater number of significant probes was identified for a given q-value cutoff for Age decline, CPD × Age decline and Baseline lung function outcomes after probe selection.