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Current clamp properties of DRG neurons transfected with WT, P1308L, or V1298F NaV1.7R construct.
| Construct | n | Rinput(MΩ) | RMP (mV) | Threshold (pA) |
|---|---|---|---|---|
| WT | 38 | 605 ± 57 | -55.9 ± 1.1 | 188 ± 14 |
| P1308L | 50 | 749 ± 70 | -52.4 ± 1.1 | 122 ± 10* |
| V1298F | 27 | 598 ± 46 | -55.1 ± 1.5 | 154 ± 18 |
* p < 0.05 vs WT NaV1.7R channels.
