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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Toxicon. 2009 Dec 7;55(4):818–826. doi: 10.1016/j.toxicon.2009.11.017

Figure 2. Inhibition of the 0831–1035 on the endopeptidase activity of BoNT/A LC.

Figure 2

Panel A: the dose-response curve for 0831–1035 mediated BoNT/A LC endopepidase inhibition. The curve was fit using non-linear polynomial regression. Panel B: Lineweaver-Burk plot of BoNT/A LC inhibition with and without inhibitor 0831–1035 (using the13-mer peptide as the substrate (see the methods for details).