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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Jun 1;878(19):1590–1598. doi: 10.1016/j.jchromb.2010.04.019

Figure 7.

Figure 7

Plots of 1/k versus [Tolbutamide] for competition studies performed by zonal elution using (a) L-tryptophan or (b) R-warfarin as site-selective probes injected onto HSA columns in the presence of various concentrations of tolbutamide as a competing agent. The equations for the best-fit lines shown in these plots are as follows: (a) y = 8400 (± 300) x + 0.157 (± 0.003), with a correlation coefficient of 0.998 (n = 6); (b) y = 1070 (± 30) x + 0.0194 (± 0.0004), with a correlation coefficient of 0.999 (n = 4). Error bars representing a range of ±1 S.D. are included in this plot but the corresponding ranges are small and not easily visible on the scale employed for this plot).