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Factors that mediate dipping and conditions that impair dipping. The 3 factors that are primarily responsible for dipping are physical activity, sodium sensitivity and autonomic function. Impairments of any of these 3 functions can lead to non-dipping. Some conditions associated with non-dipping are shown outside these circles and discussed in the text. Diseases such as CKD are often associated with non-dipping the pathophysiology of which is complex and discussed in the text.
